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Clinical trials have not shown a signal for increased thyroid cancer risk, though regulators note that the human relevance of rodent C-cell tumours is unknown and monitoring is ongoing

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The analysts' evaluation The milestone was propelled by the success of Mounjaro and Zepbound, injectables for diabetes and weight loss based on GLP-1 gut hormones, which recorded higher prescription volumes than similar drugs from competitors such as Novo Nordisk (Ozempic and Wegovy)